Metabolic Syndrome

NON ALCOHOLIC FATTY LIVER DISEASE (NAFLD)

“Non Alcoholic Fatty Liver Disease is one of the common complications of obese people with metabolic syndrome. It is very common and the incidence is rising with the incidence of obesity and metabolic syndrome. It is dangerous and can lead to chirrosis and liver failure. It will soon be the commonest cause of liver transplanation”.

Fatty liver is a condition in which the cells of the liver accumulate abnormally increased amounts of fat. Although excessive consumption of alcohol is a very common cause of fatty liver (alcoholic fatty liver), there is another form of fatty liver, termed nonalcoholic fatty liver disease (nonalcoholic fatty liver disease), in which alcohol has been excluded as a cause. In nonalcoholic fatty liver disease, other recognized causes of fatty liver that are less common causes than alcohol also are excluded.

Nonalcoholic fatty liver disease is a manifestation of an abnormality of metabolism within the liver. The liver is an important organ in the metabolism (handling) of fat. The liver makes and exports fat to other parts of the body. It also removes fat from the blood that has been released by other tissues in the body, for example, by fat cells, or absorbed from the food we eat. In nonalcoholic fatty liver disease, the handling of fat by liver cells is disturbed. Increased amounts of fat are removed from the blood and/or are produced by liver cells, and not enough is disposed of or exported by the cells. As a result, fat accumulates in the liver.

Nonalcoholic fatty liver disease is classified as either fatty liver (sometimes referred to as isolated fatty liver or IFL) or steatohepatitis (NASH). In both isolated fatty liver and NASH there is an abnormal amount of fat in the liver cells, but, in addition, in NASH there is inflammation within the liver, and, as a result, the liver cells are damaged, they die, and are replaced by scar tissue.

 

Nonalcoholic fatty liver disease is important for several reasons. First, it is a common disease, and is increasing in prevalence. Second, NASH is an important cause of serious liver disease, leading to cirrhosis and the complications of cirrhosis–liver failure, gastrointestinal bleeding, and liver cancer. Third, nonalcoholic fatty liver disease is associated with other very common and serious non-liver diseases, perhaps the most important being metabolic syndrome with the associated cardiovascular disease that leads to heart attacks and strokes. Fatty liver probably is not the cause of these other diseases, but is a manifestation of┬ámetabolic syndrome that the diseases share. Fatty liver, therefore, is a clue to the presence┬ámetabolic syndrome and the ┬áserious complications of the disease which need to be addressed.

Diabetes Mellitus type 2, Metabolic Syndrome

Diabetes Type 2 with Metabolic Syndrome: case study.


Patient is a 65 year old pathologist. Was reasonably active with cycling and horseriding. He was overweight and enjoyed a social life with a daily glass of wine and occasional beers over weekends. He experienced exercise intolerance and was on treatment for cholesterol, hypertension, gout and an arythmia that kept him awake at night. He also took one Ecotrin daily.

On 27 July he tested a continous glucose monitor for Metronic just to find out that he has an average blood glucose value of 10 mmol/ml. He was surprised because at the end of 2016 he was screened for an insurance policy and nothing was wrong.

For obvious reasons he started to study Diabetes and Metabolic Syndrome and came to the conclusion that there is no quick cure for this disease and that if he want to survive this challenge he must change his ways. He also realized that he was treating the symptoms of Metabolic Syndrome – a common mistake. (Hypertension, gout, high cholesterol and arythmia). He learned for the first time in his life that if he could control metabolic syndrome, he may not need al these chronic medications.

At this stage his clinical profile was as follow:

Weight: 117 kg.

BMI: 34,94

Fasting Blood Sugar: 9,8

HDL-cholesterol: 1,4 mmol/L

LDL-cholesterol: 3,2 mmol/L

C-reactive protein: 3,9 mg/L

HbA1c: 7,8%

Exercise History: 30 minutes cycling per week.

On 17 January 2018 after all the principles proposed by newCare innovation were applied, the following clinical criteria were observed:

Weight: 95 kg.

BMI: 28,37

Fasting Blood Sugar: 5,2

HDL-cholesterol: 1,9mmol/L

LDL-cholesterol: 2,6mmol/L

C-reactive protein: 1,6mg/L

HbA1c: 5,8%

Exercise History: Minimum of 6 hours running and cycling per week.

His excercise intolerance and activity level was exceptional and on Friday 9 March 2018 he ran 10,3 km in 1,05 hour. (Something that he last did in the army in 1971).

If you think this is exceptional you are wrong. In the most recent literature all over the world this is happening more and more. Old obese people are reviving under good advice and after aquiring the support, knowledge and skills from professional people about Metabolic Syndrome. Worst of all is that the knowledge of general practitioners and specialist about the effect and treatment of metabolic syndrome is currently limited.

He stopped all medical treatment for cholesterol, high blood pressure, arythmia and gout. He currently is just using one Ecotrin and 1 gram of Metformin per day.

When this photo was taken 3 March 2018 his weight was 86 kg. Just after the photo was taken he climbed a spoiled black arabian stallion who injured him 2 years ago; just for the challenge. It was succesful.

Metabolic Syndrome, Uncategorized

What are my chances to have metabolic syndrome????

If you have the following:

  1. BMI over 32. (BMI=Weight in kg/square of your length in meters).
  2. Abdominal circumference of over 95cm. for men and 85 cm. for women.
  3. Blood pressure of over 130/90 or on hypertension treatment.
  4. Fasting Blood glucose of over 5,8 mmol/Liter.
  5. Inactive with exercise intolerance.

If you have all 5 your chances are over 90% of having metabolic syndrome.

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